Cambridge Healthtech Institute’s 7th Annual

Optimizing Protein Expression
5-6 November 2014


This second part of the protein stream for PEGS Europe will focus on the methods and technologies for achieving the highest possible yield, with the best functionality. 

Topics will include, but are not limited to the following:


  • Selecting the correct host for your needs
  • Salvaging “gold standard” hosts for your project
  • Novel hosts
  • Bacteria, yeast, insect, mammalian, human, transgenic and plant expression

Gene Optimization

  • Mutagenesis (techniques, libraries, selection)
  • Vector systems (promoters, tags, signal sequences, chaperones)
  • Synthetic genes (codon usage, labeling, modifications, truncations)

Improving Yields and Functionality

  • Salvage strategies
  • Fine tuning vectors/clones for optimum expression
  • Engineering cell lines to improve yield>
  • Secretion or expression?

If you would like to submit a proposal to give a presentation at this meeting, please click here.

Deadline for submission is 21 March 2014  

All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program. Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact: 

Elizabeth J. Lamb
Senior Conference Director
Cambridge Healthtech Institute
Tel: 781-247-6259

If you are interested in exhibiting or sponsoring, please contact: 

Carol Dinerstein
Director, Business Development
Cambridge Healthtech Institute
Tel: 1 781-972-5471