Cambridge Healthtech Institute’s 13th Annual
Protein Stability & Formulation
Addressing Biophysical Challenges from Molecule to Delivery
19 November 2026
The Protein Stability & Formulation conference examines how to design high-concentration, long-acting formulations while preserving stability and function. Themes span aggregation, viscosity, and colloidal stability, formulation for ADCs, multispecifics and other complex modalities, and enabling diverse delivery routes including LNP and viral vector systems. Sessions will showcase stability modelling, AI/ML-driven prediction, and digital formulation workflows that streamline development and support reliable shelf life.
Coverage will include, but is not limited to:
BIOPHYSICAL CHARACTERISATION
- Biophysical challenges in high-concentration formulations
- SEC-based monitoring and orthogonal tools to map molecular-weight species
- Mechanisms of protein aggregation—mapping reversible vs. irreversible species
- In silico and experimental models for aggregation and viscosity risk prediction
- Linking biophysical properties to potency, immunogenicity, and clinical outcomes
FORMULATION STRATEGIES FOR EMERGING/COMPLEX MODALITIES AND DELIVERY ROUTES
- Formulation considerations for ADCs, radioconjugates, degraders, and other payload-bearing biologics
- Tailored formulation strategies for multispecifics, fusion proteins, and other complex constructs
- LNP, viral vectors for systemic delivery of mRNA, DNA, and gene-editing tools
- mRNA-LNP based in vivo expression of antibodies and cytokines
- Co-formulation and combination product designs
- Device-formulation interfaces for subcutaneous and alternative delivery routes
- Designing long-acting formulations for chronic indications
STABILITY MODELLING AND AI/ML-DRIVEN PREDICTION
- Machine learning models for stability prediction—long-term aggregation, chemical degradation, and shelf life
- Digital formulation workflows—integrating HTS, DoE and molecular simulation outputs
- Predictive shelf-life prediction
- Microfluidic assays for low-material-consumption stability testing
The deadline for priority consideration is 9 April 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: