Cambridge Healthtech Institute’s 7th Annual

Innovative CAR T Therapy

In vivo Cell and Gene Engineering

6 November 2024

CAR T therapy holds unprecedented promise not just for the treatment but also the irreversible curing of cancer; however, barriers include complex procedures, high cost of implementation and manufacturing, and the application to solid tumours. In vivo cell and gene engineering holds tremendous promise as the future direction for CAR Therapy. The generation of chimeric antigen receptor (CAR) T cells in vivo can be achieved by delivering mRNA in T cell-targeted lipid nanoparticles (LNPs) and in vivo programming. This exciting area will be featured at in the Innovative CAR T Therapy conference at PEGS Europe and will review innovative CAR structures, gene-editing tools, and gene delivery techniques to help design and develop new CAR constructs and engineer therapies in vivo. Various approaches and technologies will be assessed for their immunogenicity, potency, and modes of CAR delivery, both permanent and transient. This conference will examine what it will take to transform new CAR constructs and in vivo CAR therapy from proof-of-concept to a robust technology for clinical use.

Coverage will include, but is not limited to:

Designing CARs to modulate metabolism to overcome the TME
Engineering CAR design including split, remote-control, co-stim, logic-gates etc.
Enabling T cell therapy for solid tumours
Creating and optimising novel CAR constructs
Engineering and programming cell and genes in vivo
Advancing delivery using lipid nanoparticles and mRNA

The deadline for priority consideration is 29 March 2024.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation:

To submit a podium presentation, please click here.
To become a sponsor, click here.
To present a poster, click here.

For more details on the conference, please contact:

Christina Lingham
Executive Director, Conferences and Fellow
Cambridge Healthtech Institute
Phone: (+1) 508-813-7570
Email: clingham@healthtech.com

For sponsorship information, please contact:

Companies A-K
Jason Gerardi
Sr. Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5452
Email: jgerardi@healthtech.com

Companies L-Z
Ashley Parsons
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1340
Email: ashleyparsons@healthtech.com