Innovative CAR T Therapy banner

CAR T therapy holds unprecedented promise not just for the treatment but also the irreversible curing of cancer; however, barriers include complex procedures, high cost of implementation and manufacturing, and the application to solid tumours. In vivo cell and gene engineering holds tremendous promise as the future direction for CAR Therapy. The generation of chimeric antigen receptor (CAR) T cells in vivo can be achieved by delivering mRNA in T cell-targeted lipid nanoparticles (LNPs) and in vivo programming. This exciting area will be featured at in the Innovative CAR T Therapy conference at PEGS Europe and will review innovative CAR structures, gene-editing tools, and gene delivery techniques to help design and develop new CAR constructs and engineer therapies in vivo. Various approaches and technologies will be assessed for their immunogenicity, potency, and modes of CAR delivery, both permanent and transient. This conference will examine what it will take to transform new CAR constructs and in vivo CAR therapy from proof-of-concept to a robust technology for clinical use.

Scientific Advisory Board: 

Melita Irving, PhD, Group Leader, Ludwig Institute for Cancer Research, University of Lausanne 
Astero Klampatsa, PhD, Team Leader, Cancer Therapeutics, Institute of Cancer Research

Recommended Short Course*
Monday, 4 November, 14:00 – 17:00
SC6: Introduction to Immunogenicity of Biotherapeutics
*Separate registration required. See short courses page for details. All short courses take place in-person only.






For more details on the conference, please contact:

Christina Lingham
Executive Director, Conferences and Fellow
Cambridge Healthtech Institute
Phone: (+1) 508-813-7570
Email: clingham@healthtech.com

For sponsorship information, please contact:

Companies A-K
Jason Gerardi
Sr. Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5452
Email: jgerardi@healthtech.com

Companies L-Z
Ashley Parsons
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1340
Email: ashleyparsons@healthtech.com