Cambridge Healthtech Institute’s Inaugural

Engineering Conjugates

Designing the Magic Bullet

6 November 2024

The quest for safer and more efficacious targeted therapies drives the evolution of conjugates. PEGS Europe’s inaugural Engineering Conjugates conference will delve into the forefront of this rapidly advancing field. We invite speakers to showcase their strategies aimed at maximising efficacy while minimising off-target toxicities. We will explore the exciting field of novel formats and strategies for conditional payload release, new mechanisms-of-action, and innovative targeting approaches to expand the range of addressable targets. The conference will also highlight diverse payloads ranging from potent cytotoxins to immune-modulators, protein degraders, and oligonucleotides, showcasing the power of conjugates in revolutionising cancer treatment.

Coverage will include, but is not limited to:

Novel Formats and Innovative Targeting Strategies
- Targeting lower expression antigens
- Targeting intracellular antigens
- Small Proteins (peptides, bicycles, mini-proteins, nanobodies, DARPins) enhancing tumour penetration and exposure
- Glycan-targeting ADCs
- Bispecific / Biparatopic ADCs
- Novel Targets - cMET, HER3, CLDN18.2
Formats with Novel Mechanisms-of-Action
- Immune-Stimulating ADCs—cytokines, TLR agonists, or STING agonists
- Antibody-PROTAC conjugates
- Radioimmunoconjugates

Expanding the Payload/Linker Playing Field
- Novel payloads
- Dual payloads
- Beyond small molecules—proteins, peptides, protein degraders, radioligands, oligonucleotides

The deadline for priority consideration is 29 March 2024.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation:

To submit a podium presentation, please click here.
To become a sponsor, click here.
To present a poster, click here.

For more details on the conference, please contact:

Mimi Langley
Senior Conference Director
Cambridge Healthtech Institute
Phone: (+1) 781-972-5439
Email: mlangley@healthtech.com

For sponsorship information, please contact:

Companies A-K
Jason Gerardi
Sr. Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5452
Email: jgerardi@healthtech.com

Companies L-Z
Ashley Parsons
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1340
Email: ashleyparsons@healthtech.com