Cambridge Healthtech Institute’s 3rd Annual

Antibodies Against Membrane Protein Targets

New Strategies and Technologies to Accelerate the Development of Biotherapeutics against Complex GPCR and Ion Channel Targets

7 November 2024

As pharma increasingly shifts its attention to biologics, more attention is being paid to developing biotherapeutics against membrane-bound targets—and the rapid adoption of ML and other advanced computational tools offers an exciting and expanded toolkit for R&D scientists working in this space. For 2024, the 3rd Annual PEGS Europe Antibodies Against Membrane Protein Targets conference explores various antigen strategies, emerging modalities, and promising avenues for expanding the druggable space via computational tools, novel target identification methods, and advanced understandings of protein signaling. The latest advancements in antibody discovery will be covered, including in silico approaches, transgenic models, and synthetic libraries.

Coverage will include, but is not limited to:

Antigen Strategies

Comparative evaluation of antigen format performance with different antibody platforms
mRNA applications for antibody discovery
Whole-cell panning, structural surfaceomics

Emerging Modalities for Membrane Protein Targets

Conjugates and multispecifics
Intracellular antibodies
Nanobodies and miniproteins
Targeted protein degraders

Expanding the Druggable Membrane Target Space

Computational target prediction
Exoproteome profiling to identify new ligands and potential drug candidates
ML modelling of disease biologies
New understandings of the biology of GPCR and ion-channel signaling
Phenotypic screening for target ID

Antibody Discovery

Advances and applications in in silico antibody discovery and design
New and novel transgenic models
Next-generation synthetic librariesThe Future of Membrane Protein Discovery
Expanding understandings of the roles of autoantibodies in disease biology
Improved understandings of complex signaling cascades
Integrated ML models to simultaneously screen structure, signaling pathway, and MOA
Multiplexed experimentation; microfluidic-based screening
Next-generation predictions: affinity, epitope, cross-reactivity

The deadline for priority consideration is 29 March 2024.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation:

To submit a podium presentation, please click here.
To become a sponsor, click here.
To present a poster, click here.

For more details on the conference, please contact:

Kent Simmons
Senior Conference Director
Cambridge Healthtech Institute
Phone: (+1) 207-329-2964
Email: ksimmons@healthtech.com

For sponsorship information, please contact:

Companies A-K
Jason Gerardi
Sr. Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5452
Email: jgerardi@healthtech.com

Companies L-Z
Ashley Parsons
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1340
Email: ashleyparsons@healthtech.com